منابع مشابه
Regulation of heparanase gene expression by estrogen in breast cancer.
Numerous epidemiological studies clearly suggest that estrogen is one of the main driving forces in breast tumorigenesis, but precise mechanisms of cancer promotion by estrogen remain poorly understood. Classically, tumorigenic effects of estrogen have been attributed to its ability to directly promote the proliferation of breast cancer cells. In addition to abnormal proliferation, interactions...
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Objective(s): Despite the good results of anticancer activities by curcumin, there are some hurdles that limit the use of curcumin as an anticancer agent. Many methods were examined to overcome this defect like the use of the dendrosomal curcumin (DNC). There is increasing evidence that miRNAs play important roles in biological processes. In this study, we focus on the roles of microRNA-21 in t...
متن کاملOutcome of tongue cancer and early diagnosis
Back ground and Objective:Oral cancer is primarily a disease of epithelial origin. The tongue is the most common site of oral cancer. The aim of this study was to determine the frequency of tongue cancer and signs, symptoms, clinical features, and site of lesions in addition to factors affected this cancer. Materials Methods and:Twenty eight medical records of patients who a...
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Introduction: Breast cancer is the most common cause of cancer-related death among women. Recently, extremely low-frequency electromagnetic field (ELF-EMF) has been proposed as a new interfering agent with future therapeutic potentials. Many studies have revealed that cellular processes such as apoptosis in breast cancer are affected by ELF-EMFs. However, more researches are needed to clarify t...
متن کاملRegulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis.
Heparanase is an endoglycosidase which cleaves heparan sulfate (HS) and hence participates in degradation and remodeling of the extracellular matrix (ECM). Heparanase is preferentially expressed in human tumors and its over-expression in tumor cells confers an invasive phenotype in experimental animals. The enzyme also releases angiogenic factors from the ECM and thereby induces an angiogenic r...
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ژورنال
عنوان ژورنال: Cancer
سال: 2007
ISSN: 0008-543X
DOI: 10.1002/cncr.23095